STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1295ABC-1 domain protein; PFAM: protein of unknown function RIO1; ABC-1 domain protein. (485 aa)    
Predicted Functional Partners:
Msed_1237
Methyltransferase type 11; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11.
    
 
 0.840
Msed_1298
Nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase; PFAM: aldehyde dehydrogenase.
   
 
 0.607
Msed_1297
2-keto-3-deoxygalactonate kinase / 2-keto-3-deoxygluconate kinase; PFAM: PfkB domain protein.
  
  
 0.560
Msed_1296
2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase; PFAM: dihydrodipicolinate synthetase.
       0.543
soxN
Cytochrome b/b6, N-terminal domain; Appears to have a function related to Fe(II) oxidation; PFAM: Cytochrome b/b6, N-terminal domain.
 
  
 0.482
Msed_0291
PFAM: Cytochrome b/b6, N-terminal domain.
 
  
 0.471
tatC
Sec-independent protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes.
 
  
 0.434
Msed_2163
PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase.
 
    0.430
Msed_0144
Phosphopantothenate-cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein.
 
  
 0.411
Msed_0793
TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106.
 
  
 0.408
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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