Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msed_12962-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase; PFAM: dihydrodipicolinate synthetase. (289 aa)    
Predicted Functional Partners:
Msed_1297
2-keto-3-deoxygalactonate kinase / 2-keto-3-deoxygluconate kinase; PFAM: PfkB domain protein.
    
 0.985
Msed_1298
Nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase; PFAM: aldehyde dehydrogenase.
  
 
 0.979
Msed_1303
Galactonate dehydratase; PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein.
  
 
 0.923
Msed_0297
Glyceraldehyde oxidoreductase large chain; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding.
    
  0.900
Msed_0298
Glyceraldehyde oxidoreductase small chain; PFAM: ferredoxin; [2Fe-2S]-binding domain protein.
     
  0.900
Msed_0299
Glyceraldehyde oxidoreductase medium chain; PFAM: molybdopterin dehydrogenase, FAD-binding; CO dehydrogenase flavoprotein domain protein.
     
  0.900
Msed_0223
PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; Belongs to the phosphohexose mutase family.
 
  
 0.871
Msed_1412
PFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.869
gap
TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: glyceraldehyde 3-phosphate dehydrogenase; dihydrodipicolinate reductase.
 
 
 0.867
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.864
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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