STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
fdhDFormate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (254 aa)    
Predicted Functional Partners:
Msed_1318
TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region.
 
  
 0.970
Msed_0645
Molybdopterin synthase subunit MoaD / molybdopterin synthase subunit MoaE; TIGRFAM: MoaD family protein; PFAM: molybdopterin biosynthesis MoaE protein; thiamineS protein.
     
 0.963
Msed_1319
PFAM: protein of unknown function DUF1641.
     
 0.916
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
  
  
 0.652
Msed_1902
NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I).
     
 0.632
Msed_2024
Molybdopterin-guanine dinucleotide biosynthesis protein A-like protein.
   
 
 0.587
Msed_1545
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
       0.575
Msed_1457
TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region.
 
  
 0.530
Msed_0882
Assimilatory nitrate reductase (ferredoxin) precursor; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region.
 
  
 0.490
Msed_1450
N-terminal domain of molybdenum-binding protein-like protein.
 
   
 0.442
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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