STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Msed_1351Thiaminase / 4-amino-5-aminomethyl-2-methylpyrimidine deaminase; PFAM: TENA/THI-4 domain protein. (226 aa)    
Predicted Functional Partners:
Msed_0646
TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1.
 
 0.996
Msed_0184
TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1.
  
 0.988
Msed_0906
Hydroxymethylpyrimidine synthase; PFAM: thiamine biosynthesis protein ThiC.
  
  
 0.826
Msed_1880
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein.
 
  
 0.769
Msed_0564
Conserved hypothetical protein.
  
  
 0.760
Msed_1416
PFAM: thiamineS protein.
  
    0.733
Msed_1350
Hypothetical protein.
       0.458
Msed_0847
PFAM: cobalt transport protein.
  
  
 0.444
Msed_1034
PFAM: cobalt transport protein.
  
  
 0.444
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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