STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
Msed_1360Putative membrane protein. (239 aa)    
Predicted Functional Partners:
Msed_1075
PFAM: Squalene/phytoene synthase.
 
   
 0.727
Msed_1359
PFAM: major facilitator superfamily MFS_1.
       0.631
Msed_1358
5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase.
       0.592
Msed_1073
TIGRFAM: Phytoene dehydrogenase-related protein; PFAM: amine oxidase; FAD dependent oxidoreductase.
 
   
 0.574
carB
TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; RimK domain protein ATP-grasp; Belongs to the CarB family.
      
 0.490
Msed_1357
Conserved hypothetical protein.
       0.473
Msed_1447
Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; TC 2.A.3.
  
     0.442
Msed_1933
Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
 
   
 0.439
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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