Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1376PFAM: binding-protein-dependent transport systems inner membrane component. (538 aa)    
Predicted Functional Partners:
Msed_1377
PFAM: ABC transporter related.
 
   
 0.984
Msed_0586
Conserved hypothetical protein.
 
   
 0.858
Msed_0419
PFAM: major facilitator superfamily MFS_1.
  
     0.576
Msed_1252
PFAM: major facilitator superfamily MFS_1.
  
     0.557
Msed_0258
PFAM: major facilitator superfamily MFS_1.
  
     0.544
Msed_0588
Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; TC 2.A.3.
 
     0.532
Msed_0802
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
  
     0.531
Msed_1447
Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; TC 2.A.3.
 
     0.531
Msed_0409
Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; TC 2.A.3.
 
     0.530
Msed_1080
Glutamine amidotransferase-like protein.
  
     0.519
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.