Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Msed_1413Hypothetical protein. (169 aa)    
Predicted Functional Partners:
Msed_1414
D-proline dehydrogenase; PFAM: FAD dependent oxidoreductase.
       0.880
Msed_1415
Hypothetical protein.
       0.880
Msed_1416
PFAM: thiamineS protein.
       0.865
Msed_1412
PFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
       0.790
Msed_1417
Glycogen synthase (ADP-glucose/UDP-glucose); PFAM: glycosyl transferase, group 1; Starch synthase catalytic domain protein.
       0.661
Msed_1418
Alpha-amylase; PFAM: glycoside hydrolase, family 57.
       0.661
Msed_1411
PFAM: GCN5-related N-acetyltransferase.
       0.572
Msed_1419
PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase.
       0.492
Msed_1420
Glucoamylase; PFAM: glycoside hydrolase 15-related.
       0.492
Msed_1421
TIGRFAM: glycogen debranching enzyme, putative; PFAM: Amylo-alpha-1,6-glucosidase.
       0.492
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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