STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Msed_1414D-proline dehydrogenase; PFAM: FAD dependent oxidoreductase. (368 aa)    
Predicted Functional Partners:
Msed_1416
PFAM: thiamineS protein.
  
  
 0.963
Msed_1415
Hypothetical protein.
       0.942
Msed_1413
Hypothetical protein.
       0.880
Msed_1417
Glycogen synthase (ADP-glucose/UDP-glucose); PFAM: glycosyl transferase, group 1; Starch synthase catalytic domain protein.
 
     0.841
Msed_1418
Alpha-amylase; PFAM: glycoside hydrolase, family 57.
 
     0.827
Msed_1663
Aminomethyltransferase; TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel.
  
 
 0.741
Msed_1412
PFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.685
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 
 0.658
Msed_1419
PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase.
       0.594
Msed_1420
Glucoamylase; PFAM: glycoside hydrolase 15-related.
       0.594
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.