STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1416PFAM: thiamineS protein. (68 aa)    
Predicted Functional Partners:
Msed_1414
D-proline dehydrogenase; PFAM: FAD dependent oxidoreductase.
  
  
 0.963
Msed_1880
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein.
  
 
 0.945
Msed_1415
Hypothetical protein.
       0.933
Msed_2114
Hypothetical protein.
  
 
 0.915
Msed_0906
Hydroxymethylpyrimidine synthase; PFAM: thiamine biosynthesis protein ThiC.
  
  
 0.903
Msed_0645
Molybdopterin synthase subunit MoaD / molybdopterin synthase subunit MoaE; TIGRFAM: MoaD family protein; PFAM: molybdopterin biosynthesis MoaE protein; thiamineS protein.
     
 0.895
Msed_1413
Hypothetical protein.
       0.865
Msed_1417
Glycogen synthase (ADP-glucose/UDP-glucose); PFAM: glycosyl transferase, group 1; Starch synthase catalytic domain protein.
       0.790
Msed_1418
Alpha-amylase; PFAM: glycoside hydrolase, family 57.
       0.790
Msed_1877
TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; NADP oxidoreductase, coenzyme F420-dependent; Shikimate/quinate 5-dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
       0.789
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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