STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1433Hydrogenase 4 membrane component (E)-like protein. (209 aa)    
Predicted Functional Partners:
Msed_1432
Formate hydrogenlyase subunit 4-like protein.
 
  
 0.982
Msed_1429
PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa.
 
  
 0.975
Msed_1431
PFAM: NADH/Ubiquinone/plastoquinone (complex I).
 
  
 0.970
Msed_1430
PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit.
 
  
 0.966
Msed_1428
PFAM: NADH/Ubiquinone/plastoquinone (complex I).
 
  
 0.958
Msed_1902
NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I).
 
  
 0.956
Msed_1457
TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region.
 
   
 0.793
Msed_0569
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
  
     0.528
Msed_0802
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
  
     0.495
soxL
Rieske (2Fe-2S) domain protein; Appears to have a function related to Fe(II) oxidation; PFAM: Rieske [2Fe-2S] domain protein.
  
     0.480
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.