Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1464Hypothetical protein. (304 aa)    
Predicted Functional Partners:
Msed_1465
PFAM: protein of unknown function DUF224, cysteine-rich region domain protein.
       0.675
Msed_1466
PFAM: protein of unknown function DUF162.
       0.675
Msed_1110
TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase, IS605 OrfB.
  
     0.591
Msed_0588
Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; TC 2.A.3.
  
     0.575
Msed_1369
Physarolisin II, Serine peptidase, MEROPS family S53; PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin.
  
     0.571
Msed_1467
Aconitase; TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein.
       0.506
Msed_1368
Hypothetical protein.
  
     0.494
Msed_1067
PFAM: major facilitator superfamily MFS_1.
  
     0.493
Msed_0250
Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: amino acid permease-associated region; TC 2.A.3.
  
     0.481
Msed_1780
Tungstate/molybdate binding protein.
  
     0.471
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.