STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1492PFAM: von Willebrand factor, type A. (383 aa)    
Predicted Functional Partners:
Msed_1490
FHA domain containing protein; PFAM: Forkhead-associated protein.
 
  
 0.974
Msed_1491
PFAM: metallophosphoesterase; SMART: serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase.
 
     0.866
Msed_2088
Protoporphyrin IX magnesium-chelatase; PFAM: magnesium chelatase, ChlI subunit; von Willebrand factor, type A; SMART: AAA ATPase.
 
 
 0.808
Msed_1797
PFAM: protein kinase; SMART: serine/threonine protein kinase.
 
     0.645
Msed_0329
PFAM: protein kinase; SMART: serine/threonine protein kinase.
 
     0.621
Msed_1489
Hypothetical protein.
       0.526
Msed_0833
PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase.
 
   
 0.493
Msed_0863
PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase.
 
     0.474
Msed_2089
Cobaltochelatase CobN subunit; PFAM: CobN/magnesium chelatase.
 
 
 0.468
Msed_0310
PFAM: major facilitator superfamily MFS_1.
  
     0.467
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.