STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Msed_1509PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (327 aa)    
Predicted Functional Partners:
Msed_1902
NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I).
  
  
 0.859
Msed_1177
PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase.
 
 
 0.821
Msed_0455
PFAM: Lactate/malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 
 0.764
Msed_0916
Hydrogenase 2 maturation peptidase, Aspartic peptidase, MEROPS family A31; TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52, hydrogen uptake protein.
   
 
 0.712
Msed_2256
PFAM: peptidylprolyl isomerase, FKBP-type.
  
    0.697
Msed_1091
Dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
  
 0.684
Msed_1551
Dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
  
 0.658
ppa
Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
   
 
 0.623
Msed_0703
TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase.
  
  
 0.621
Msed_1506
PFAM: biotin/lipoate A/B protein ligase.
 
    0.614
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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