STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1522TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase. (370 aa)    
Predicted Functional Partners:
Msed_1467
Aconitase; TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein.
 
 0.998
Msed_0455
PFAM: Lactate/malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.997
Msed_0278
2-methylcitrate dehydratase; PFAM: MmgE/PrpD family protein.
 
 
 0.983
Msed_1462
Fumarase; PFAM: fumarate lyase.
  
 0.982
Msed_1375
Acetyl-CoA/propionyl-CoA carboxylase; PFAM: carboxyl transferase.
  
 
 0.969
Msed_1042
PFAM: malate synthase.
  
 0.966
Msed_1582
succinyl-CoA synthetase (ADP-forming) beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein.
  
 0.961
Msed_0270
Acetyl-CoA acetyltransferase-like protein.
  
 0.959
Msed_0271
Acetyl-CoA acetyltransferase-like protein.
  
 0.959
Msed_0386
Propanoyl-CoA C-acyltransferase; PFAM: Thiolase.
  
 0.959
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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