STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1526Phosphohydrolase (DHH superfamily)-like protein. (323 aa)    
Predicted Functional Partners:
Msed_1527
PFAM: isochorismatase hydrolase.
       0.882
Msed_1584
PFAM: Glycosyltransferase 28, C-terminal domain.
 
     0.650
Msed_1365
PFAM: tyrosine specific protein phosphatase; Dual specificity protein phosphatase; SMART: protein tyrosine phosphatase, catalytic region.
 
     0.625
Msed_1528
PFAM: protein of unknown function DUF214.
       0.593
Msed_0667
SMART: von Willebrand factor, type A.
  
     0.583
nfi
Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
       0.576
Msed_0651
PFAM: type II secretion system protein.
  
     0.573
Msed_1529
Hypothetical protein.
       0.547
Msed_1682
Dehydrogenase (flavoprotein)-like protein.
  
     0.544
Msed_1661
PFAM: protein of unknown function DUF75.
  
     0.537
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.