STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1527PFAM: isochorismatase hydrolase. (199 aa)    
Predicted Functional Partners:
Msed_1526
Phosphohydrolase (DHH superfamily)-like protein.
       0.882
nfi
Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
 
     0.676
Msed_1528
PFAM: protein of unknown function DUF214.
     
 0.659
Msed_1623
PFAM: Quinolinate phosphoribosyl transferase.
 
  
 0.628
Msed_1525
1-Cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.615
Msed_1365
PFAM: tyrosine specific protein phosphatase; Dual specificity protein phosphatase; SMART: protein tyrosine phosphatase, catalytic region.
  
    0.610
Msed_0430
PFAM: isochorismatase hydrolase.
  
     0.607
Msed_1529
Hypothetical protein.
       0.600
Msed_1083
Hypothetical protein.
 
  
 0.431
Msed_1292
PFAM: SMP-30/Gluconolaconase/LRE domain protein.
  
    0.428
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.