STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1540PFAM: sodium/calcium exchanger membrane region. (305 aa)    
Predicted Functional Partners:
Msed_0645
Molybdopterin synthase subunit MoaD / molybdopterin synthase subunit MoaE; TIGRFAM: MoaD family protein; PFAM: molybdopterin biosynthesis MoaE protein; thiamineS protein.
  
    0.706
Msed_1544
Hypothetical protein.
 
     0.578
Msed_1543
Heterodisulfide reductase subunit C-like protein.
 
     0.518
Msed_1541
PFAM: protein of unknown function DUF202.
       0.514
Msed_1545
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
     0.512
Msed_1778
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
   0.486
Msed_0125
Conserved hypothetical protein.
  
     0.478
Msed_1546
PFAM: protein of unknown function DUF224, cysteine-rich region domain protein.
 
     0.461
Msed_1805
PFAM: Oligosaccharyl transferase, STT3 subunit.
  
     0.460
Msed_2164
PFAM: protein of unknown function DUF87.
 
     0.452
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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