STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1542CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224, cysteine-rich region domain protein. (306 aa)    
Predicted Functional Partners:
Msed_1545
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
 0.999
Msed_1543
Heterodisulfide reductase subunit C-like protein.
 
 0.998
Msed_1547
Heterodisulfide reductase subunit C-like protein.
 
  
 0.994
Msed_1546
PFAM: protein of unknown function DUF224, cysteine-rich region domain protein.
 
  
  0.985
Msed_1544
Hypothetical protein.
 
     0.959
Msed_0920
Coenzyme F420-reducing hydrogenase alpha subunit-like protein.
  
 
 0.856
Msed_1541
PFAM: protein of unknown function DUF202.
 
     0.730
Msed_1550
PFAM: DsrE family protein.
 
  
 0.593
Msed_0923
PFAM: nickel-dependent hydrogenase, large subunit.
  
 
 0.592
Msed_0945
Ni Fe-hydrogenase I large subunit-like protein.
  
 
 0.592
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.