STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1545PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (365 aa)    
Predicted Functional Partners:
Msed_1542
CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224, cysteine-rich region domain protein.
 
 0.999
Msed_1543
Heterodisulfide reductase subunit C-like protein.
 
 0.998
Msed_1546
PFAM: protein of unknown function DUF224, cysteine-rich region domain protein.
 
 0.998
Msed_1547
Heterodisulfide reductase subunit C-like protein.
 
 0.996
Msed_1544
Hypothetical protein.
 
     0.958
Msed_0675
Succinate dehydrogenase subunit C; PFAM: protein of unknown function DUF224, cysteine-rich region domain protein.
 
 
 0.937
gcvH-3
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
  
  
 0.799
Msed_0814
Anaerobic dehydrogenase typically selenocysteine-containing-like protein.
 
 
 0.797
Msed_0920
Coenzyme F420-reducing hydrogenase alpha subunit-like protein.
  
 
 0.794
Msed_0923
PFAM: nickel-dependent hydrogenase, large subunit.
  
 
 0.794
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.