STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1556PFAM: histone deacetylase superfamily. (341 aa)    
Predicted Functional Partners:
Msed_1557
Hypothetical protein.
       0.795
Msed_1558
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
       0.784
Msed_1559
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
       0.781
Msed_1560
PFAM: biotin/lipoate A/B protein ligase.
       0.780
rpl40e
PFAM: ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
   
  0.768
Msed_0596
TBP-interacting protein TIP49; PFAM: TIP49-like; SMART: AAA ATPase.
  
 
 0.730
cobB
Silent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily.
   
 
 0.704
Msed_0634
PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; Belongs to the AAA ATPase family.
 
 
 0.673
Msed_0210
TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein; AAA ATPase, central domain protein; cell division protein 48, CDC48, domain 2; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase.
   
 0.630
Msed_0470
PFAM: AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase.
   
 0.630
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.