node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Msed_0253 | ogt | Msed_0253 | Msed_1586 | PFAM: UspA domain protein. | methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.621 |
Msed_1017 | ogt | Msed_1017 | Msed_1586 | PFAM: UspA domain protein. | methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.621 |
Msed_1582 | Msed_1583 | Msed_1582 | Msed_1583 | succinyl-CoA synthetase (ADP-forming) beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein. | DNA-3-methyladenine glycosylase III; SMART: HhH-GPD family protein. | 0.800 |
Msed_1582 | Msed_1584 | Msed_1582 | Msed_1584 | succinyl-CoA synthetase (ADP-forming) beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein. | PFAM: Glycosyltransferase 28, C-terminal domain. | 0.799 |
Msed_1582 | ogt | Msed_1582 | Msed_1586 | succinyl-CoA synthetase (ADP-forming) beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein. | methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.605 |
Msed_1582 | thrS-cat | Msed_1582 | Msed_1585 | succinyl-CoA synthetase (ADP-forming) beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein. | threonyl-tRNA synthetase / Ser-tRNA(Thr) hydrolase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also activates L-serine and transfers it to tRNA(Thr) but cannot deacylate incorrectly charged amino acid; unlike most archaea the editing function is found in a freestanding protein. | 0.674 |
Msed_1583 | Msed_1582 | Msed_1583 | Msed_1582 | DNA-3-methyladenine glycosylase III; SMART: HhH-GPD family protein. | succinyl-CoA synthetase (ADP-forming) beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein. | 0.800 |
Msed_1583 | Msed_1584 | Msed_1583 | Msed_1584 | DNA-3-methyladenine glycosylase III; SMART: HhH-GPD family protein. | PFAM: Glycosyltransferase 28, C-terminal domain. | 0.831 |
Msed_1583 | ogt | Msed_1583 | Msed_1586 | DNA-3-methyladenine glycosylase III; SMART: HhH-GPD family protein. | methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.643 |
Msed_1583 | thrS-cat | Msed_1583 | Msed_1585 | DNA-3-methyladenine glycosylase III; SMART: HhH-GPD family protein. | threonyl-tRNA synthetase / Ser-tRNA(Thr) hydrolase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also activates L-serine and transfers it to tRNA(Thr) but cannot deacylate incorrectly charged amino acid; unlike most archaea the editing function is found in a freestanding protein. | 0.603 |
Msed_1584 | Msed_1582 | Msed_1584 | Msed_1582 | PFAM: Glycosyltransferase 28, C-terminal domain. | succinyl-CoA synthetase (ADP-forming) beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein. | 0.799 |
Msed_1584 | Msed_1583 | Msed_1584 | Msed_1583 | PFAM: Glycosyltransferase 28, C-terminal domain. | DNA-3-methyladenine glycosylase III; SMART: HhH-GPD family protein. | 0.831 |
Msed_1584 | Msed_1651 | Msed_1584 | Msed_1651 | PFAM: Glycosyltransferase 28, C-terminal domain. | PFAM: UspA domain protein. | 0.488 |
Msed_1584 | ogt | Msed_1584 | Msed_1586 | PFAM: Glycosyltransferase 28, C-terminal domain. | methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.643 |
Msed_1584 | thrS-cat | Msed_1584 | Msed_1585 | PFAM: Glycosyltransferase 28, C-terminal domain. | threonyl-tRNA synthetase / Ser-tRNA(Thr) hydrolase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also activates L-serine and transfers it to tRNA(Thr) but cannot deacylate incorrectly charged amino acid; unlike most archaea the editing function is found in a freestanding protein. | 0.629 |
Msed_1589 | ogt | Msed_1589 | Msed_1586 | PFAM: UspA domain protein. | methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.621 |
Msed_1651 | Msed_1584 | Msed_1651 | Msed_1584 | PFAM: UspA domain protein. | PFAM: Glycosyltransferase 28, C-terminal domain. | 0.488 |
Msed_1651 | ogt | Msed_1651 | Msed_1586 | PFAM: UspA domain protein. | methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.621 |
Msed_2008 | ogt | Msed_2008 | Msed_1586 | PFAM: UspA domain protein. | methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.621 |
Msed_2110 | ogt | Msed_2110 | Msed_1586 | DNA-(apurinic or apyrimidinic site) lyase; PFAM: HhH-GPD family protein; SMART: iron-sulfur cluster loop. | methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.545 |