STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msed_1597Thiamine pyrophosphate enzyme domain protein TPP-binding protein; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (607 aa)    
Predicted Functional Partners:
Msed_1596
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase.
 
 
 0.995
Msed_0677
TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.789
Msed_1114
TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein.
  
 
 0.789
Msed_1399
PFAM: CoA-binding domain protein.
   
 
 0.722
Msed_0507
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase.
 
 
 0.633
Msed_1598
PFAM: helix-turn-helix domain protein.
 
     0.579
Msed_0306
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase.
  
 
 0.576
Msed_2074
Glutamate dehydrogenase (NAD/NADP); PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.572
Msed_0468
Putative signal-transduction protein with CBS domains; PFAM: CBS domain containing protein; 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
     
 0.553
cysN
Sulfate adenylyltransferase; Appears to have a role in S metabolism; PFAM: ATP-sulfurylase.
  
  
 0.546
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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