STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
nacNascent polypeptide associated complex NAC; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. (115 aa)    
Predicted Functional Partners:
rps3ae
PFAM: ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
   
 
 0.969
rps24e
SSU ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family.
   
 
 0.967
rps3
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
 
 
 0.964
rps10
SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
   0.963
rps19e
SSU ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
  
   0.962
rpl29
PFAM: ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
  
   0.957
rpl5
LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
 
 
 0.957
rpl15e
PFAM: ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.
 
   0.956
rps4e
PFAM: RNA-binding S4 domain protein; ribosomal protein S4E-like; ribosomal protein S4E, central; Belongs to the eukaryotic ribosomal protein eS4 family.
 
   0.956
rps6e
PFAM: ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
  
   0.956
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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