Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1682Dehydrogenase (flavoprotein)-like protein. (325 aa)    
Predicted Functional Partners:
Msed_1681
Hypothetical protein.
       0.916
Msed_1680
Hypothetical protein.
       0.886
Msed_0331
PFAM: electron transfer flavoprotein beta-subunit.
  
 
 0.657
Msed_2082
SMART: AAA ATPase.
 
     0.600
Msed_1683
TIGRFAM: valyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.587
Msed_0224
PFAM: protein of unknown function DUF343.
  
     0.584
slaB
Hypothetical protein; S-layer small protein. May anchor the complex to the cell membrane.
  
     0.568
Msed_1250
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
  
 
 0.563
Msed_0334
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
  
 
 0.561
Msed_0651
PFAM: type II secretion system protein.
 
     0.552
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
Server load: medium (42%) [HD]