| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Msed_0033 | Msed_0034 | Msed_0033 | Msed_0034 | DNA-directed RNA polymerase, subunit B' / DNA-directed RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| Msed_0033 | Msed_1733 | Msed_0033 | Msed_1733 | DNA-directed RNA polymerase, subunit B' / DNA-directed RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | PFAM: Zinc finger, TFIIB-type domain protein; Transcription factor TFIIB, cyclin-related; SMART: Cyclin. | 0.876 |
| Msed_0033 | rpoA2 | Msed_0033 | Msed_0035 | DNA-directed RNA polymerase, subunit B' / DNA-directed RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| Msed_0033 | rpoD | Msed_0033 | Msed_2145 | DNA-directed RNA polymerase, subunit B' / DNA-directed RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| Msed_0033 | rpoH | Msed_0033 | Msed_0032 | DNA-directed RNA polymerase, subunit B' / DNA-directed RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.999 |
| Msed_0033 | rpoK | Msed_0033 | Msed_1673 | DNA-directed RNA polymerase, subunit B' / DNA-directed RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. | 0.998 |
| Msed_0033 | rpoN | Msed_0033 | Msed_2141 | DNA-directed RNA polymerase, subunit B' / DNA-directed RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. | 0.994 |
| Msed_0033 | tbp | Msed_0033 | Msed_1728 | DNA-directed RNA polymerase, subunit B' / DNA-directed RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | TATA binding protein of transcription factor TFIID; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. | 0.963 |
| Msed_0033 | tfb | Msed_0033 | Msed_2209 | DNA-directed RNA polymerase, subunit B' / DNA-directed RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcription initiation factor IIB (TFIIB); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). | 0.902 |
| Msed_0033 | tfe | Msed_0033 | Msed_2279 | DNA-directed RNA polymerase, subunit B' / DNA-directed RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcription factor IIE (TFIIE), alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elo [...] | 0.963 |
| Msed_0034 | Msed_0033 | Msed_0034 | Msed_0033 | DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, subunit B' / DNA-directed RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| Msed_0034 | Msed_1733 | Msed_0034 | Msed_1733 | DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | PFAM: Zinc finger, TFIIB-type domain protein; Transcription factor TFIIB, cyclin-related; SMART: Cyclin. | 0.636 |
| Msed_0034 | rpoA2 | Msed_0034 | Msed_0035 | DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| Msed_0034 | rpoD | Msed_0034 | Msed_2145 | DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| Msed_0034 | rpoH | Msed_0034 | Msed_0032 | DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.999 |
| Msed_0034 | rpoK | Msed_0034 | Msed_1673 | DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. | 0.996 |
| Msed_0034 | rpoN | Msed_0034 | Msed_2141 | DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. | 0.993 |
| Msed_0034 | tbp | Msed_0034 | Msed_1728 | DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | TATA binding protein of transcription factor TFIID; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. | 0.963 |
| Msed_0034 | tfb | Msed_0034 | Msed_2209 | DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcription initiation factor IIB (TFIIB); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). | 0.647 |
| Msed_0034 | tfe | Msed_0034 | Msed_2279 | DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcription factor IIE (TFIIE), alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elo [...] | 0.870 |
