STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1731Uncharacterized coiled-coil protein-like protein. (302 aa)    
Predicted Functional Partners:
Msed_1730
PFAM: protein of unknown function DUF373.
 
     0.948
Msed_1399
PFAM: CoA-binding domain protein.
       0.846
Msed_0669
PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type.
 
     0.648
taw3
Conserved hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family.
  
     0.610
Msed_2035
PFAM: Sjogrens syndrome scleroderma autoantigen 1.
  
     0.601
Msed_1672
PFAM: AAA ATPase, central domain protein; MIT; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase.
 
   
 0.568
Msed_1526
Phosphohydrolase (DHH superfamily)-like protein.
  
     0.526
Msed_0537
Hypothetical protein.
  
     0.521
Msed_2046
ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication.
  
     0.500
Msed_0556
PFAM: Cobyrinic acid a,c-diamide synthase.
      
 0.497
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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