STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Msed_1775TIGRFAM: 3,4-dihydroxyphenylacetate 2,3-dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. (314 aa)    
Predicted Functional Partners:
Msed_1776
PFAM: 4-hydroxyphenylacetate 3-hydroxylase.
 
   
 0.897
Msed_1777
PFAM: fumarylacetoacetate (FAA) hydrolase.
  
  
 0.800
Msed_1899
TIGRFAM: NADH-quinone oxidoreductase, chain I; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
  
  
 0.734
Msed_1226
TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase.
  
  
 0.704
Msed_1897
PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa; Belongs to the complex I 49 kDa subunit family.
  
  
 0.688
Msed_1774
PFAM: aldehyde dehydrogenase.
  
 
 0.684
Msed_1113
PFAM: succinate dehydrogenase, cytochrome b subunit.
  
  
 0.683
Msed_0996
4-hydroxyphenylacetate 3-monooxygenase oxygenase component; PFAM: 4-hydroxyphenylacetate 3-hydroxylase.
 
   
 0.575
Msed_0676
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
  
  
 0.497
Msed_0677
TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.496
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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