STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Msed_1777PFAM: fumarylacetoacetate (FAA) hydrolase. (284 aa)    
Predicted Functional Partners:
Msed_1775
TIGRFAM: 3,4-dihydroxyphenylacetate 2,3-dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
  
  
 0.800
Msed_1776
PFAM: 4-hydroxyphenylacetate 3-hydroxylase.
  
  
 0.795
Msed_1774
PFAM: aldehyde dehydrogenase.
  
 
 0.661
Msed_0415
PFAM: NADH:flavin oxidoreductase/NADH oxidase.
  
  
 0.469
Msed_1458
PFAM: Aldose 1-epimerase.
 
    0.446
Msed_0995
TIGRFAM: 3,4-dihydroxyphenylacetate 2,3-dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
  
  
 0.425
Msed_0275
4-aminobutyrate aminotransferase apoenzyme; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.419
Msed_0700
PFAM: transcriptional coactivator/pterin dehydratase.
  
  
 0.417
gap
TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: glyceraldehyde 3-phosphate dehydrogenase; dihydrodipicolinate reductase.
 
 
 0.412
Msed_0996
4-hydroxyphenylacetate 3-monooxygenase oxygenase component; PFAM: 4-hydroxyphenylacetate 3-hydroxylase.
  
  
 0.411
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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