STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Msed_1778PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (243 aa)    
Predicted Functional Partners:
Msed_1779
PFAM: TatD-related deoxyribonuclease.
       0.893
Msed_0415
PFAM: NADH:flavin oxidoreductase/NADH oxidase.
  
  
 0.791
Msed_2072
PFAM: short-chain dehydrogenase/reductase SDR.
 
 
 0.772
Msed_1224
PFAM: AMP-dependent synthetase and ligase; regulatory protein, ArsR.
  
 
 0.675
Msed_0394
AMP-dependent synthetase and ligase; Catalyzes the ligation of coenzyme A (CoA) to 4- hydroxybutyrate (4HB). It can also use butyrate, valerate, propionate, acetate and 3-hydroxybutyrate (3HB) as substrates.
  
 
 0.636
Msed_0401
PFAM: AMP-dependent synthetase and ligase.
  
 
 0.636
Msed_1015
PFAM: AMP-dependent synthetase and ligase.
  
 
 0.636
Msed_1615
PFAM: AMP-dependent synthetase and ligase.
  
 
 0.636
Msed_1781
PFAM: binding-protein-dependent transport systems inner membrane component.
  
    0.618
Msed_1780
Tungstate/molybdate binding protein.
       0.579
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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