STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
slaBHypothetical protein; S-layer small protein. May anchor the complex to the cell membrane. (416 aa)    
Predicted Functional Partners:
slaA
Hypothetical protein; S-layer large protein. May form the highly ordered outer sheath.
     
 0.859
Msed_1805
PFAM: Oligosaccharyl transferase, STT3 subunit.
 
     0.622
Msed_1682
Dehydrogenase (flavoprotein)-like protein.
  
     0.568
Msed_0619
PFAM: regulatory protein, AsnC/Lrp family.
  
     0.511
Msed_1783
Ser/Thr protein kinase-like protein.
  
     0.502
Msed_1808
PFAM: glycosyl transferase, group 1.
       0.482
Msed_0224
PFAM: protein of unknown function DUF343.
  
     0.462
Msed_1907
PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B.
  
     0.454
hypA
Hydrogenase expression/synthesis, HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
     0.436
Msed_1393
PFAM: peptidase M28.
  
     0.427
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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