Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1811UDP-glucose pyrophosphorylase; PFAM: Nucleotidyl transferase. (255 aa)    
Predicted Functional Partners:
Msed_1810
PFAM: UDP-glucose/GDP-mannose dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein.
 
 0.996
Msed_1604
PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase.
 
  
 0.953
Msed_0174
PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain.
 
 
 0.952
Msed_0068
PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase.
 
  
 0.946
Msed_1845
TIGRFAM: glucose-1-phosphate thymidyltransferase; PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase.
 
 
0.945
Msed_0223
PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; Belongs to the phosphohexose mutase family.
    
 0.939
Msed_0241
UDP-sulfoquinovose synthase; PFAM: NAD-dependent epimerase/dehydratase.
  
 
 0.922
Msed_0129
Trehalose synthase (ADP-glucose); PFAM: glycosyl transferase, group 1.
    
 0.916
Msed_1809
PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain.
 
  
 0.862
Msed_1890
PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase.
 
  
0.860
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
Server load: low (26%) [HD]