node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Msed_0223 | Msed_0597 | Msed_0223 | Msed_0597 | PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; Belongs to the phosphohexose mutase family. | PFAM: PfkB domain protein. | 0.924 |
Msed_0223 | Msed_1878 | Msed_0223 | Msed_1878 | PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; Belongs to the phosphohexose mutase family. | Transketolase subunit B; PFAM: Transketolase, central region; Transketolase domain protein. | 0.905 |
Msed_0223 | Msed_1879 | Msed_0223 | Msed_1879 | PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; Belongs to the phosphohexose mutase family. | PFAM: Transketolase domain protein. | 0.916 |
Msed_0223 | Msed_2287 | Msed_0223 | Msed_2287 | PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; Belongs to the phosphohexose mutase family. | TIGRFAM: ribose 5-phosphate isomerase; PFAM: Ribose 5-phosphate isomerase. | 0.950 |
Msed_0223 | pdxS | Msed_0223 | Msed_1923 | PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; Belongs to the phosphohexose mutase family. | Pyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.800 |
Msed_0223 | pdxT | Msed_0223 | Msed_1924 | PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; Belongs to the phosphohexose mutase family. | Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.800 |
Msed_0223 | prs | Msed_0223 | Msed_1790 | PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; Belongs to the phosphohexose mutase family. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | 0.969 |
Msed_0223 | rbsK | Msed_0223 | Msed_0185 | PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; Belongs to the phosphohexose mutase family. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.924 |
Msed_0597 | Msed_0223 | Msed_0597 | Msed_0223 | PFAM: PfkB domain protein. | PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; Belongs to the phosphohexose mutase family. | 0.924 |
Msed_0597 | Msed_1878 | Msed_0597 | Msed_1878 | PFAM: PfkB domain protein. | Transketolase subunit B; PFAM: Transketolase, central region; Transketolase domain protein. | 0.919 |
Msed_0597 | Msed_1879 | Msed_0597 | Msed_1879 | PFAM: PfkB domain protein. | PFAM: Transketolase domain protein. | 0.917 |
Msed_0597 | Msed_2287 | Msed_0597 | Msed_2287 | PFAM: PfkB domain protein. | TIGRFAM: ribose 5-phosphate isomerase; PFAM: Ribose 5-phosphate isomerase. | 0.922 |
Msed_0597 | pdxS | Msed_0597 | Msed_1923 | PFAM: PfkB domain protein. | Pyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.833 |
Msed_0597 | pdxT | Msed_0597 | Msed_1924 | PFAM: PfkB domain protein. | Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.830 |
Msed_0597 | prs | Msed_0597 | Msed_1790 | PFAM: PfkB domain protein. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | 0.939 |
Msed_0597 | rbsK | Msed_0597 | Msed_0185 | PFAM: PfkB domain protein. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.925 |
Msed_1878 | Msed_0223 | Msed_1878 | Msed_0223 | Transketolase subunit B; PFAM: Transketolase, central region; Transketolase domain protein. | PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; Belongs to the phosphohexose mutase family. | 0.905 |
Msed_1878 | Msed_0597 | Msed_1878 | Msed_0597 | Transketolase subunit B; PFAM: Transketolase, central region; Transketolase domain protein. | PFAM: PfkB domain protein. | 0.919 |
Msed_1878 | Msed_1879 | Msed_1878 | Msed_1879 | Transketolase subunit B; PFAM: Transketolase, central region; Transketolase domain protein. | PFAM: Transketolase domain protein. | 0.999 |
Msed_1878 | Msed_2287 | Msed_1878 | Msed_2287 | Transketolase subunit B; PFAM: Transketolase, central region; Transketolase domain protein. | TIGRFAM: ribose 5-phosphate isomerase; PFAM: Ribose 5-phosphate isomerase. | 0.920 |