STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
argHTIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase. (448 aa)    
Predicted Functional Partners:
argG
PFAM: argininosuccinate synthase; ExsB family protein; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
 
 0.999
carB
TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; RimK domain protein ATP-grasp; Belongs to the CarB family.
  
  
 0.987
carA
TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; Belongs to the CarA family.
 
  
 0.984
lysZ
N-acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily.
 
  
 0.969
Msed_1703
TIGRFAM: ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
 
  
 0.965
lysY
N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
 
  
 0.956
lysJ
Acetylornithine aminotransferase apoenzyme / N2-acetyl-L-lysine aminotransferase apoenzyme; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
 
  
 0.956
Msed_1991
L-2-aminoadipate N-acetyltransferase; TIGRFAM: alpha-L-glutamate ligase, RimK family; lysine biosynthesis enzyme LysX; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp.
     
 0.947
Msed_0874
Arginine deiminase; PFAM: amidinotransferase.
    
 0.931
Msed_0018
TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
    
 0.927
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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