STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_1992PFAM: Translin. (204 aa)    
Predicted Functional Partners:
ribK
CTP-dependent riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
     
 0.706
Msed_1993
3-hydroxypropionate dehydrogenase (NADP(+)); PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
       0.604
Msed_2034
PFAM: protein of unknown function UPF0147; Belongs to the UPF0147 family.
 
     0.499
Msed_1736
FMN adenylyltransferase; TIGRFAM: cytidyltransferase-related domain; PFAM: cytidylyltransferase; protein of unknown function DUF357.
      
 0.483
Msed_2137
Isopentenyl phosphate kinase; PFAM: aspartate/glutamate/uridylate kinase.
 
     0.477
Msed_1648
PFAM: protein of unknown function DUF35.
  
     0.474
Msed_1787
PFAM: protein of unknown function DUF54; Belongs to the UPF0201 family.
 
     0.472
Msed_0622
Zn-dependent hydrolase of the beta-lactamase fold-like protein.
 
     0.456
nfi
Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
       0.453
taw1
Wyosine base formation; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
       0.453
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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