Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msed_2005Transcriptional regulator, CopG family; PFAM: CopG domain protein DNA-binding domain protein. (128 aa)    
Predicted Functional Partners:
Msed_2003
PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding.
 
     0.925
Msed_2004
Phosphoenolpyruvate synthase; PFAM: B3/4 domain protein.
       0.913
Msed_0888
TIGRFAM: urease, beta subunit; urease, gamma subunit; PFAM: Urease, beta subunit; Urease, gamma subunit region.
     
 0.743
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
       0.710
Msed_2007
PFAM: peptidase U62, modulator of DNA gyrase.
  
    0.632
Msed_2006
PFAM: peptidase U62, modulator of DNA gyrase.
     
 0.622
Msed_2008
PFAM: UspA domain protein.
  
    0.465
hypA
Hydrogenase expression/synthesis, HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
     
 0.455
Msed_0441
ABC-type dipeptide transport system periplasmic component-like protein.
 
   
 0.411
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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