STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Msed_2005Transcriptional regulator, CopG family; PFAM: CopG domain protein DNA-binding domain protein. (128 aa)    
Predicted Functional Partners:
Msed_2003
PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding.
 
     0.828
Msed_2004
Phosphoenolpyruvate synthase; PFAM: B3/4 domain protein.
       0.799
Msed_0888
TIGRFAM: urease, beta subunit; urease, gamma subunit; PFAM: Urease, beta subunit; Urease, gamma subunit region.
     
 0.719
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
       0.708
Msed_2007
PFAM: peptidase U62, modulator of DNA gyrase.
  
    0.622
Msed_2006
PFAM: peptidase U62, modulator of DNA gyrase.
     
 0.611
Msed_2008
PFAM: UspA domain protein.
  
    0.466
Msed_2009
Pyridine nucleotide-disulfide oxidoreductase dimerization region; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
    0.423
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
     
 0.422
Msed_0441
ABC-type dipeptide transport system periplasmic component-like protein.
 
   
 0.421
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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