STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Msed_2013Glycerate 2-kinase; PFAM: MOFRL domain protein. (395 aa)    
Predicted Functional Partners:
Msed_0256
Glyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
 
 0.956
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.944
Msed_0297
Glyceraldehyde oxidoreductase large chain; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding.
 
  
 0.913
Msed_0299
Glyceraldehyde oxidoreductase medium chain; PFAM: molybdopterin dehydrogenase, FAD-binding; CO dehydrogenase flavoprotein domain protein.
    
 0.903
Msed_0298
Glyceraldehyde oxidoreductase small chain; PFAM: ferredoxin; [2Fe-2S]-binding domain protein.
    
  0.900
Msed_0773
PFAM: Phosphoglycerate mutase.
     
  0.900
apgM
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
     
  0.900
Msed_1412
PFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.886
gap
TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: glyceraldehyde 3-phosphate dehydrogenase; dihydrodipicolinate reductase.
 
 
  0.839
Msed_1856
TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase.
    
 0.838
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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