STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Msed_2016FeoA family protein; PFAM: regulatory protein, MarR; iron dependent repressor; FeoA family protein. (213 aa)    
Predicted Functional Partners:
Msed_2013
Glycerate 2-kinase; PFAM: MOFRL domain protein.
       0.799
Msed_2015
Hypothetical protein.
       0.799
Msed_2017
Hypothetical protein.
       0.785
Msed_2014
PFAM: major facilitator superfamily MFS_1.
  
    0.780
Msed_0767
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator.
  
  
 0.671
Msed_1430
PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit.
  
 
   0.648
Msed_0974
Hypothetical protein.
 
  
 0.585
Msed_2018
Hypothetical protein.
       0.583
Msed_2019
Hypothetical protein.
       0.580
cobB
Silent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily.
 
    0.485
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.