Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msed_2020PFAM: Methyltransferase type 11; Methyltransferase type 12. (230 aa)    
Predicted Functional Partners:
Msed_2022
TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region.
       0.836
Msed_2021
Putative signal-transduction protein with CBS domains; PFAM: CBS domain containing protein.
  
   0.817
rps5
SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
    
 0.786
Msed_2012
TIGRFAM: NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; Belongs to the complex I 20 kDa subunit family.
   
 0.720
Msed_1897
PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa; Belongs to the complex I 49 kDa subunit family.
    
 0.703
Msed_1896
TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C; PFAM: NADH dehydrogenase (ubiquinone), 30 kDa subunit.
   
 0.681
Msed_1494
PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like.
 
 0.674
Msed_2024
Molybdopterin-guanine dinucleotide biosynthesis protein A-like protein.
 
     0.668
rps9
PFAM: ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
    
  0.664
Msed_1075
PFAM: Squalene/phytoene synthase.
   
 0.656
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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