STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_2111PFAM: ParB domain protein nuclease. (193 aa)    
Predicted Functional Partners:
Msed_2112
PFAM: glycosyl transferase, family 2.
     
 0.948
Msed_2110
DNA-(apurinic or apyrimidinic site) lyase; PFAM: HhH-GPD family protein; SMART: iron-sulfur cluster loop.
     
 0.939
Msed_2113
ATP dependent helicase, Lhr family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases-like.
     
 0.859
Msed_0011
L-threonine ammonia-lyase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
  
 
 0.852
Msed_2003
PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding.
    
  0.813
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
     
  0.800
Msed_0234
Hypothetical protein.
 
 
 0.741
Msed_0556
PFAM: Cobyrinic acid a,c-diamide synthase.
 
 
 0.729
Msed_0517
Uncharacterized flavoprotein-like protein.
  
 
 0.722
Msed_0248
Hypothetical protein.
  
 
 0.692
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.