STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msed_2120Putative transcriptional regulator, GntR family; PFAM: aminotransferase, class I and II. (401 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.918
Msed_0602
PFAM: glutamine synthetase, catalytic region.
    
 0.913
Msed_1612
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp.
    
 0.913
Msed_0256
Glyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
  
 
  0.911
Msed_0892
Transcriptional regulator, GntR family; PFAM: aminotransferase, class I and II.
  
  
 
0.907
Msed_0436
D-lactate dehydrogenase; PFAM: FAD linked oxidase domain protein.
    
 0.904
Msed_0552
PFAM: FAD linked oxidase domain protein.
    
 0.904
Msed_0553
PFAM: FAD linked oxidase domain protein.
    
 0.904
Msed_1118
D-lactate dehydrogenase; PFAM: FAD linked oxidase domain protein.
    
 0.904
Msed_0168
L-2-aminoadipate N-acetyltransferase; TIGRFAM: alpha-L-glutamate ligase, RimK family; lysine biosynthesis enzyme LysX; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp.
    
  0.900
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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