STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Msed_2159Nucleotidyltransferase-like protein. (223 aa)    
Predicted Functional Partners:
Msed_2157
PFAM: Radical SAM domain protein.
 
     0.824
Msed_2158
PFAM: uncharacterised conserved protein UCP017998.
       0.800
Msed_2160
PFAM: peptidase M50; SMART: PDZ/DHR/GLGF domain protein.
 
     0.714
Msed_0584
Predicted hydrolase of the metallo-beta-lactamase superfamily; Belongs to the UPF0282 family.
  
     0.612
Msed_2035
PFAM: Sjogrens syndrome scleroderma autoantigen 1.
 
     0.608
Msed_2127
Conserved hypothetical protein.
  
     0.577
Msed_0204
Transcription elongation factor-like protein.
  
     0.574
pcn
DNA polymerase sliding clamp subunit B; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
  
     0.565
nep1
Suppressor Mra1; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
  
     0.513
Msed_1907
PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B.
 
     0.483
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.