node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Msed_1710 | Msed_2264 | Msed_1710 | Msed_2264 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | 0.873 |
Msed_1710 | ef1b | Msed_1710 | Msed_0209 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | Translation elongation factor 1B (aEF-1B); Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. | 0.433 |
Msed_1710 | fen | Msed_1710 | Msed_0212 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] | 0.778 |
Msed_1710 | pan | Msed_1710 | Msed_2275 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.439 |
Msed_1710 | psmA | Msed_1710 | Msed_0074 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.784 |
Msed_1710 | psmB1 | Msed_1710 | Msed_2052 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | Proteasome endopeptidase complex, beta component, Threonine peptidase, MEROPS family T01A; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.611 |
Msed_1710 | psmB2 | Msed_1710 | Msed_2268 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | Proteasome endopeptidase complex, beta component, Threonine peptidase, MEROPS family T01A; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.765 |
Msed_1710 | rpl4 | Msed_1710 | Msed_0092 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | LSU ribosomal protein L4P; Forms part of the polypeptide exit tunnel. | 0.815 |
Msed_2114 | pan | Msed_2114 | Msed_2275 | Hypothetical protein. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.999 |
Msed_2114 | psmA | Msed_2114 | Msed_0074 | Hypothetical protein. | Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.886 |
Msed_2114 | psmB1 | Msed_2114 | Msed_2052 | Hypothetical protein. | Proteasome endopeptidase complex, beta component, Threonine peptidase, MEROPS family T01A; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.886 |
Msed_2114 | psmB2 | Msed_2114 | Msed_2268 | Hypothetical protein. | Proteasome endopeptidase complex, beta component, Threonine peptidase, MEROPS family T01A; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.886 |
Msed_2114 | rpl40e | Msed_2114 | Msed_0203 | Hypothetical protein. | PFAM: ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.967 |
Msed_2264 | Msed_1710 | Msed_2264 | Msed_1710 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | 0.873 |
Msed_2264 | ef1b | Msed_2264 | Msed_0209 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | Translation elongation factor 1B (aEF-1B); Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. | 0.418 |
Msed_2264 | fen | Msed_2264 | Msed_0212 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] | 0.745 |
Msed_2264 | pan | Msed_2264 | Msed_2275 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.439 |
Msed_2264 | psmA | Msed_2264 | Msed_0074 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.752 |
Msed_2264 | psmB1 | Msed_2264 | Msed_2052 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | Proteasome endopeptidase complex, beta component, Threonine peptidase, MEROPS family T01A; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.629 |
Msed_2264 | psmB2 | Msed_2264 | Msed_2268 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | Proteasome endopeptidase complex, beta component, Threonine peptidase, MEROPS family T01A; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.791 |