STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smar_1256rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC; KEGG: ape:APE2199 nucleolar protein NOP5. (409 aa)    
Predicted Functional Partners:
rpl7ae
LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
 0.999
nep1
Suppressor Mra1; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
  
 
 0.999
tmcA
Protein of unknown function DUF699, ATPase putative; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
  
 
 0.999
flpA
rRNA 2'-O-methyltransferase fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
 
 
 0.999
rps6e
PFAM: ribosomal protein S6e; KEGG: sso:SSO0411 30S ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
  
  0.992
rps4
SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 0.987
rps11
SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
  
  0.986
Smar_1107
PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: ape:APE0754 mitochondrial-type HSP70.
  
 
 0.975
csl4
RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.
   
  0.967
Smar_0934
TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; Nucleolar GTP-binding 1; KEGG: pfu:PF1495 GTP-binding protein, gtp1/obg family.
   
 
 0.966
Your Current Organism:
Staphylothermus marinus
NCBI taxonomy Id: 399550
Other names: S. marinus F1, Staphylothermus marinus ATCC 43588, Staphylothermus marinus DSM 3639, Staphylothermus marinus F1, Staphylothermus marinus JCM 9404, Staphylothermus marinus str. F1, Staphylothermus marinus strain F1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.