STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smar_1490TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; KEGG: oih:OB1764 biotin [acetyl-CoA carboxylase] ligase. (303 aa)    
Predicted Functional Partners:
Smar_0140
Pyruvate carboxylase subunit A; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; RimK domain protein ATP-grasp; KEGG: afu:AF0220 pyruvate carboxylase subunit A.
 
 0.999
Smar_1426
PFAM: carboxyl transferase; KEGG: pho:PH1287 methylmalonyl-CoA decarboxylase alpha chain.
 
 
 0.999
Smar_0190
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: pfu:PF0144 biotin synthetase.
     
  0.900
Smar_1489
PFAM: protein of unknown function UPF0153; KEGG: pai:PAE0937 hypothetical protein.
       0.888
Smar_1427
PFAM: biotin/lipoyl attachment domain-containing protein; glycine cleavage H-protein; KEGG: sso:SSO2464 Biotin carboxyl carrier protein of propionyl-CoA carboxylase beta subunit.
   
 
 0.862
Smar_1488
TIGRFAM: cytidyltransferase-related domain; PFAM: cytidylyltransferase; KEGG: ape:APE1986 hypothetical protein.
     
 0.846
Smar_1186
PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sso:SSO0556 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, putataive; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
  
 0.555
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
 
  
 0.549
Smar_1487
PFAM: peptidase M50; KEGG: sai:Saci_0440 peptidase family M50 protein.
       0.543
Smar_0561
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pfu:PF0149 putative alcohol dehydrogenase/reductase.
 
  
 0.481
Your Current Organism:
Staphylothermus marinus
NCBI taxonomy Id: 399550
Other names: S. marinus F1, Staphylothermus marinus ATCC 43588, Staphylothermus marinus DSM 3639, Staphylothermus marinus F1, Staphylothermus marinus JCM 9404, Staphylothermus marinus str. F1, Staphylothermus marinus strain F1
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