STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hgd3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (298 aa)    
Predicted Functional Partners:
echA8_1
Enoyl-CoA hydratase/carnithine racemase.
 
 0.993
acsB
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 
  0.926
mmsA
Methylmalonate-semialdehyde dehydrogenase.
 
 
 0.907
yfcX
Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.807
fadB
3-hydroxyacyl CoA dehydrogenase oxidoreductase protein; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.807
garR
3-hydroxyisobutyrate dehydrogenase.
  
  
 
0.729
ydiJ
Oxidase.
    
  0.728
Lmor_0998
D-isomer specific 2-hydroxyacid dehydrogenase.
 
  
  0.698
gabD-2
Piperidine-6-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.659
calB
Alcohol dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.659
Your Current Organism:
Legionella moravica
NCBI taxonomy Id: 39962
Other names: ATCC 43877, CCUG 31117, CIP 103883, DSM 19234, L. moravica, NCTC 12239, strain 316-36
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