ytfL protein (Legionella moravica) - STRING interaction network

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[Homology]

Score

ytfL

Metal ion transporter. (444 aa)

Predicted Functional Partners:

guaA

0.833

rdgB

0.574

coq7

0.568

nnr

0.568

ushA

0.558

Lmor_2907

0.540

Lmor_2021

0.529

purA

0.528

purH

0.522

ppt_1

0.511

Your Current Organism:

Legionella moravica

NCBI taxonomy Id: 39962
Other names: ATCC 43877, CCUG 31117, CIP 103883, DSM 19234, L. moravica, NCTC 12239, strain 316-36

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lmor_2021	Lmor_2907	Lmor_2021	Lmor_2907	Dipeptidyl aminopeptidase/acylaminoacyl peptidase.	Saframycin Mx1 synthetase B.	0.780
Lmor_2021	ytfL	Lmor_2021	Lmor_2020	Dipeptidyl aminopeptidase/acylaminoacyl peptidase.	Metal ion transporter.	0.529
Lmor_2907	Lmor_2021	Lmor_2907	Lmor_2021	Saframycin Mx1 synthetase B.	Dipeptidyl aminopeptidase/acylaminoacyl peptidase.	0.780
Lmor_2907	purH	Lmor_2907	Lmor_2100	Saframycin Mx1 synthetase B.	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.	0.438
Lmor_2907	ytfL	Lmor_2907	Lmor_2020	Saframycin Mx1 synthetase B.	Metal ion transporter.	0.540
coq7	ytfL	Lmor_0189	Lmor_2020	Ubiquinone biosynthesis protein COQ7; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.	Metal ion transporter.	0.568
guaA	ppt_1	Lmor_2413	Lmor_1087	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Hypoxanthine-guanine phosphoribosyltransferase.	0.924
guaA	purA	Lmor_2413	Lmor_2124	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.958
guaA	purH	Lmor_2413	Lmor_2100	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.	0.962
guaA	rdgB	Lmor_2413	Lmor_0125	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.947
guaA	ushA	Lmor_2413	Lmor_1424	GMP synthase; Catalyzes the synthesis of GMP from XMP.	5'-nucleotidase; Belongs to the 5'-nucleotidase family.	0.637
guaA	ytfL	Lmor_2413	Lmor_2020	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Metal ion transporter.	0.833
nnr	purA	Lmor_1400	Lmor_2124	Sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of [...]	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.616
nnr	ytfL	Lmor_1400	Lmor_2020	Sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of [...]	Metal ion transporter.	0.568
ppt_1	guaA	Lmor_1087	Lmor_2413	Hypoxanthine-guanine phosphoribosyltransferase.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.924
ppt_1	purA	Lmor_1087	Lmor_2124	Hypoxanthine-guanine phosphoribosyltransferase.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.899
ppt_1	purH	Lmor_1087	Lmor_2100	Hypoxanthine-guanine phosphoribosyltransferase.	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.	0.915
ppt_1	rdgB	Lmor_1087	Lmor_0125	Hypoxanthine-guanine phosphoribosyltransferase.	Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.861
ppt_1	ushA	Lmor_1087	Lmor_1424	Hypoxanthine-guanine phosphoribosyltransferase.	5'-nucleotidase; Belongs to the 5'-nucleotidase family.	0.521
ppt_1	ytfL	Lmor_1087	Lmor_2020	Hypoxanthine-guanine phosphoribosyltransferase.	Metal ion transporter.	0.511