node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADE13 | ADE17 | A0A369J8W6 | A0A369J1U4 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Bifunctional purine biosynthesis protein ADE17. | 0.989 |
ADE13 | ADK | A0A369J8W6 | A0A369K488 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenosine kinase. | 0.965 |
ADE13 | ADK1 | A0A369J8W6 | A0A369JXD5 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. | 0.949 |
ADE13 | APT1 | A0A369J8W6 | A0A369JJU6 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenine phosphoribosyltransferase. | 0.972 |
ADE13 | Hypma_009223 | A0A369J8W6 | A0A369JRL2 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.867 |
ADE13 | Hypma_009737 | A0A369J8W6 | A0A369JNY4 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.993 |
ADE13 | Hypma_013012 | A0A369J8W6 | A0A369JDB4 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.405 |
ADE13 | YND1 | A0A369J8W6 | A0A369JIY1 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Golgi apyrase; Belongs to the GDA1/CD39 NTPase family. | 0.915 |
ADE13 | ada1 | A0A369J8W6 | A0A369J2C9 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.933 |
ADE13 | yfkN | A0A369J8W6 | A0A369JNQ3 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Trifunctional nucleotide phosphoesterase protein YfkN; Belongs to the 5'-nucleotidase family. | 0.923 |
ADE17 | ADE13 | A0A369J1U4 | A0A369J8W6 | Bifunctional purine biosynthesis protein ADE17. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.989 |
ADE17 | ADK | A0A369J1U4 | A0A369K488 | Bifunctional purine biosynthesis protein ADE17. | Adenosine kinase. | 0.692 |
ADE17 | ADK1 | A0A369J1U4 | A0A369JXD5 | Bifunctional purine biosynthesis protein ADE17. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. | 0.664 |
ADE17 | APT1 | A0A369J1U4 | A0A369JJU6 | Bifunctional purine biosynthesis protein ADE17. | Adenine phosphoribosyltransferase. | 0.969 |
ADE17 | Hypma_009223 | A0A369J1U4 | A0A369JRL2 | Bifunctional purine biosynthesis protein ADE17. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.968 |
ADE17 | Hypma_009737 | A0A369J1U4 | A0A369JNY4 | Bifunctional purine biosynthesis protein ADE17. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.987 |
ADE17 | Hypma_013012 | A0A369J1U4 | A0A369JDB4 | Bifunctional purine biosynthesis protein ADE17. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.945 |
ADE17 | YND1 | A0A369J1U4 | A0A369JIY1 | Bifunctional purine biosynthesis protein ADE17. | Golgi apyrase; Belongs to the GDA1/CD39 NTPase family. | 0.934 |
ADE17 | ada1 | A0A369J1U4 | A0A369J2C9 | Bifunctional purine biosynthesis protein ADE17. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.926 |
ADE17 | yfkN | A0A369J1U4 | A0A369JNQ3 | Bifunctional purine biosynthesis protein ADE17. | Trifunctional nucleotide phosphoesterase protein YfkN; Belongs to the 5'-nucleotidase family. | 0.928 |