STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ergic3Endoplasmic reticulum-Golgi intermediate compartment protein 3. (423 aa)    
Predicted Functional Partners:
erv41
ER-derived vesicles protein 41.
  
 
0.983
gtpbp3
tRNA modification GTPase GTPBP3, mitochondrial.
  
 0.930
Hypma_012000
G domain-containing protein.
  
 0.930
Vps45
Vacuolar protein sorting-associated protein 45; Belongs to the STXBP/unc-18/SEC1 family.
 
      0.900
mnmA
tRNA-specific 2-thiouridylase MnmA.
  
 0.793
SPCS1
Signal peptidase complex subunit 1.
    
   0.609
ero-1
Endoplasmic reticulum oxidoreductin-1.
    
   0.608
Hypma_012031
Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family.
   
 
 0.575
TYS1
Tyrosine--tRNA ligase.
     
 0.494
OXA1L
Mitochondrial inner membrane protein OXA1L.
  
  
 0.485
Your Current Organism:
Hypsizygus marmoreus
NCBI taxonomy Id: 39966
Other names: H. marmoreus
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.