STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hypma_001206Uncharacterized protein. (656 aa)    
Predicted Functional Partners:
UFD4
Ubiquitin fusion degradation protein 4.
   
 
 0.775
UBIQ
Ubiquitin.
   
 0.725
Hypma_010088
Uncharacterized protein.
    
 0.693
rrn7
RNA polymerase I-specific transcription initiation factor rrn7.
    
 0.693
Hypma_000125
Uncharacterized protein.
    
 0.693
ATG7
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
    
 0.648
tef3
Elongation factor 3.
   
   0.642
uba3
NEDD8-activating enzyme E1 catalytic subunit.
    
 0.630
Hypma_013724
Uncharacterized protein.
   
 0.622
Hypma_013723
Uncharacterized protein.
   
 0.622
Your Current Organism:
Hypsizygus marmoreus
NCBI taxonomy Id: 39966
Other names: H. marmoreus
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