node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DRE2 | Hypma_000791 | A0A369JWT9 | A0A369JG56 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.839 |
HMOX2 | Hypma_000791 | A0A369J2E7 | A0A369JG56 | Heme oxygenase 2. | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.856 |
HMOX2 | YAH1 | A0A369J2E7 | A0A369K983 | Heme oxygenase 2. | Adrenodoxin, mitochondrial. | 0.716 |
HMT-1 | Hypma_000791 | A0A369JD22 | A0A369JG56 | Homocysteine S-methyltransferase 1. | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.781 |
HMT-1 | sir1 | A0A369JD22 | A0A369JMQ8 | Homocysteine S-methyltransferase 1. | Sulfite reductase [NADPH] subunit beta. | 0.430 |
Hypma_000791 | DRE2 | A0A369JG56 | A0A369JWT9 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | 0.839 |
Hypma_000791 | HMOX2 | A0A369JG56 | A0A369J2E7 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Heme oxygenase 2. | 0.856 |
Hypma_000791 | HMT-1 | A0A369JG56 | A0A369JD22 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Homocysteine S-methyltransferase 1. | 0.781 |
Hypma_000791 | Hypma_013684 | A0A369JG56 | A0A369JC51 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.866 |
Hypma_000791 | Hypma_013686 | A0A369JG56 | A0A369JBG4 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.913 |
Hypma_000791 | NAR1_1 | A0A369JG56 | A0A369KD47 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria. | 0.867 |
Hypma_000791 | YAH1 | A0A369JG56 | A0A369K983 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Adrenodoxin, mitochondrial. | 0.835 |
Hypma_000791 | met14 | A0A369JG56 | A0A369J7U0 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.794 |
Hypma_000791 | sA | A0A369JG56 | A0A369JJE8 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Phosphoadenosine phosphosulfate reductase. | 0.747 |
Hypma_000791 | sir1 | A0A369JG56 | A0A369JMQ8 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Sulfite reductase [NADPH] subunit beta. | 0.961 |
Hypma_013684 | Hypma_000791 | A0A369JC51 | A0A369JG56 | Uncharacterized protein; Belongs to the cytochrome P450 family. | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.866 |
Hypma_013684 | NAR1_1 | A0A369JC51 | A0A369KD47 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria. | 0.672 |
Hypma_013684 | YAH1 | A0A369JC51 | A0A369K983 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Adrenodoxin, mitochondrial. | 0.497 |
Hypma_013686 | Hypma_000791 | A0A369JBG4 | A0A369JG56 | Uncharacterized protein; Belongs to the cytochrome P450 family. | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.913 |
Hypma_013686 | NAR1_1 | A0A369JBG4 | A0A369KD47 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria. | 0.672 |