STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hypma_000791NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (754 aa)    
Predicted Functional Partners:
sir1
Sulfite reductase [NADPH] subunit beta.
 
0.961
Hypma_013686
Uncharacterized protein; Belongs to the cytochrome P450 family.
 
  
 
 0.913
NAR1_1
Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
    
 0.867
Hypma_013684
Uncharacterized protein; Belongs to the cytochrome P450 family.
 
  
 
 0.866
HMOX2
Heme oxygenase 2.
    
 
 0.856
DRE2
Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...]
    
 0.839
YAH1
Adrenodoxin, mitochondrial.
   
 0.835
met14
Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate.
  
  
 0.794
HMT-1
Homocysteine S-methyltransferase 1.
  
 0.781
sA
Phosphoadenosine phosphosulfate reductase.
  
 
 0.747
Your Current Organism:
Hypsizygus marmoreus
NCBI taxonomy Id: 39966
Other names: H. marmoreus
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